Clinically tested.

KIOS® has been evaluated at five distinct study sites including our most recent study at a walk-in clinic with a Medicaid eligible population in Paducah, KY. 

The Cecil Clinic Trial

PADUCAH, KENTUCKY

The Cecil Clinic offers walk-in care to a wide range of patients, many of whom are Medicaid eligible. Twelve bipolar patients from the Cecil Clinic completed a 3-month study of KIOS. 

Within the first week, patients experienced
an average reduction in symptoms as follows:

Depression symptoms

31%

manic symptoms

17%

instability symptoms*

24%

 *anxiety, irratibility, and shifting emotions

The downloadable report provides timely, specific, and valuable information that I can use to better treat a person suffering from bipolar disorder. But…what I like most is the visible improvement that I see when a patient returns to my clinic after he/she has been using KIOS.

- Dr. John Cecil

The Cecil clinic, paducah kentucky

By day 60, patients experienced
an average reduction in symptoms as follows:

Depression symptoms

41%

manic symptoms

46%

instability symptoms

39%

Bexar County Mental Health Court

SAN ANTONIO, TEXAS

KIOS was tested in a population of bipolar patients on probation for misdemeanors from the Bexar County Mental Health Court. 

Over the course of the 12 week study, patients using KIOS experienced a statistically significant (p<0.001)…

38%

REDUCTION IN OVERALL BIPOLAR SYMPTOMS

10 of 16

PARTICIPANTS ASKED AND CONTINUED TO USE KIOS VOLUNTARILY AFTER COMPLETING THE TRIAL WITHOUT INCENTIVES

Trials at Three University Clinics

funded by the national institutes of mental health

KIOS was tested in a one-year study at University of Texas Health Science Center – San Antonio under the direction of Charles L. Bowden, MD, The University of Cincinnati Lindner Center of Hope under the direction of Susan L. McElroy, MD, and the University of Louisville under the direction of Rif S. Al-Mallakh, MD. 

In this multi-site study, funded by the National Institute of Mental Health, patients using KIOS experienced a statistically significant reduction in bipolar symptoms over the first sixteen weeks of the study that persisted until the end of the year long trial. 

90%

OF THE PATIENTS USING KIOS COMPLETED THE STUDY, DEMONSTRATING LONG-TERM COMPLIANCE AND USABILITY. 

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¹ Research reported in this publication was supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number R42MH091997. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

² This technology was supported in part by an award from the Kentucky Cabinet for Economic Development, Office of Entrepreneurship, under the Grant Agreement KSTC-184-512-15-223 with the Kentucky Science and Technology Corporation